Preparation and characterization of doxorubicin HCl loadedchitosan nanoparticles by w/o emulsion method

Abstract

Controlled and specific medication delivery using polymeric nanoparticles has received considerable
attention lately. The goal of this research was to create doxorubicin-loaded chitosan nanoparticles and test
their efficacy. Nanoparticles lacked aggregation, according to scanning electron microscopy. There was no
evidence of a chemical reaction between the medication and polymer in the FTIR spectra. Research
conducted in vitro on medication release has provided evidence that it is possible to prolong drug release.
Drug release studies demonstrate the prolonged release after vigorous agitation produces nano-sized
particles.