A preliminary investigation on alterations in basic metabolic profiles to assess the possible effectiveness of dietary ginger on ethanol-induced oxidative stress in rat cardiac tissue.

Abstract

This study set out to determine how ginger (Zingiber officinale) may shield rat heart cells from the
damaging effects of alcohol. Total carbs, pyruvate, total proteins, free amino acids, and lactate levels were
assessed in cardiac tissue to characterize the carbohydrate metabolic profiles. Rats that had consumed too
much alcohol had significantly lower levels of free amino acids and lactate and significantly lower amounts
of total carbs and pyruvate. Total glucose, protein, and pyruvate levels were found to be significantly higher
in cardiac tissues treated with ginger (200 mg/kg body weight), whereas free amino acid and lactate levels
were found to be significantly lower. The results of the current research suggest that ginger's high
concentration of bioactive chemicals is responsible for its protective effect on cardiac tissue against alcohol
poisoning in rats.