Investigation of the Phytochemical Components, Antimicrobial Actions, and Impact of Pycanthus Angolensis Weld Warb Exudate on Corneal Ulcers in Rabbits (Myristicaceae)

Abstract

For the purpose of treating corneal ulcers, a combination of 1 part Anchomonas difformis, 1 part Cyrtrospherma
senegalense, and 2 parts Pycanthus angolensis has been proposed. In accordance with claims made in traditional
medicine, this research will assess the phytochemical components, antibacterial activity, and efficacy of a
combination of these exudates in treating corneal ulcers. The method included collecting fresh exudates in separate
containers. After they were dried off, the phytochemical components of each residue were examined. We further
investigated the antibacterial properties of P. angolensis exudates by studying their impact on rabbits with
chemically produced ocular ulcers. The results showed that the exudates of A. angolensis and C. senegalensis
contained only reducing sugars. Tannins, flavonoids, and reducing sugars were the bioactive components found
in P. angolensis exudates. Additionally, this demonstrated antibacterial action against the tested species. Within
ten days of therapy, it cured the corneal ulcers in rabbits that had been caused by NaOH. In conclusion, the corneal
ulcers in rabbits were cured by the exudates of P.angolensis, which included bioactive components and showed
antibacterial activity. Even without A. angolensis and C. senegalensis exudates, its traditional usage for healing
corneal ulcers seems reasonable.