Vitex leucoxylon Linn. leaf extracts inhibit inflammation in vitro by stabilizing red blood cell membranes.

Abstract

Various functions of hydro alcoholic extract and ethanolic extract of the Vitex leucoxylon Linn. leaves of were
screened for anti-inflammatory activity by human red blood cell (HRBC) membrane stabilization method. The
prevention of hypotonicity-induced HRBC membrane lysis was taken as a measure of the anti- inflammatory
activity. All the fractions showed a biphasic effect on the membrane stabilization. Their activities are comparable
to that of the standard drug prednisolone. However their activities decreased with time.