Dissolvable atenolol tablet formulation and efficacy assessment

Abstract

In an effort to improve patient adherence, direct compression technique atenolol pills were developed.
Croscarmelose sodium and sodium starch glycolate were the two super disintegrants tested here.
Tablets were tested for consistency in weight, thickness, hardness, friability, wetting time, water
absorption ratio, disintegration time, and dissolution studies after being manufactured in batches. The
tablets were likewise manufactured using the identical excipients, but were tested without dis
integrants. Based on the data, it seems that tablet formulation (A4) is the most viable option. Standard
limitations were also met for the tablets' hardness, friability, disintegration time, and dissolution rate
during preparation.