Instamodel for the study of the impact of matrix dosage forms on the release of diclofenac sodium

Abstract

Instamodel is a polymer that is used in the formulation development of matrix based tablet as sustained release drug
delivery system includes all the dosage forms formulated to retard the release of the therapeutic agent such that its
appearance in the systemic circulation is delayed and/or prolonged and its plasma profile is sustained in duration the
onset of drugs pharmacologic action is often delayed and the duration of drugs therapeutic effects is sustained. Now a
day, matrix and micro encapsulation is the most frequently employed method of producing sustained release dosage
forms. Over the few decades’ enormous progress has been made in developing these two technologies and applying it
to diverse field of medical and other usage. In the following article mode formulation and various other evaluation
parameter are discussed and finally shown the effect of their concentration on the drug release profile.