Synthesis, Characterization and Antimicrobial Activity of Zinc Oxide Nanoparticles Synthesized From Calotropis procera

Abstract

Nanoparticles generated from Calotropis procera leaf extract were compared for their quantity, nature, and antibacterial action in this
work. The generated ZnO NPs were examined using FTIR and SEM. Images captured by scanning electron microscopy clearly show
that the biologically produced particles have a size between 100 and 200 nm. The minimum inhibitory concentration (MIC) values of
several antibacterial agents were determined by conducting studies on both plant and human diseases. The green produced ZnO NPs
exhibited strong antibacterial activity against both human and plant pathogens at all doses tested, with the highest zone of inhibition
seen at 30 μg/mL. At concentrations ranging from 50 to 12.5 εg/ml of nano-ZnO, all microorganisms tested were entirely inhibited,
according to the Minimum Inhibitory Concentrations of NPs against human pathogenic bacteria and plant bacterial pathogens. Various
concentrations of ZnO nanoparticles significantly inhibited spore germination, demonstrating the antifungal action of these particles
against fungus.